Alyssa Tsai

Founder & General Partner, mshrmm
Founder, PANONY and PANews
Limited Partner, Animoca Brands Β· NGC Ventures Β· Delta Blockchain Fund
Forbes 30 Under 30 Asia 2020
Forbes 30 Under 30 China 2020

Alyssa Tsai is the Founder and General Partner of mshrmm, a venture capital firm focused on artificial intelligence, decentralized infrastructure, and next-generation technologies. She is also the Co-Founder of PANONY and PANews, one of Asia's leading Web3 media and strategic advisory platforms. Under her leadership, the group has supported over 500 blockchain projects and advised institutions including Amazon Web Services, Ant Financial (Alibaba Group), and major digital asset exchanges on go-to-market and ecosystem development.

Recognized by Forbes 30 Under 30 Asia and Forbes 30 Under 30 China, Tsai bridges early-stage innovation with institutional capital. Through mshrmm, she invests in foundational technologies shaping the future of value creation and digital infrastructure.

She serves as a mentor to the Harvard Blockchain Association and has contributed to multiple accelerator programs. Tsai frequently delivers private briefings for global banks and family offices, and speaks at industry forums including Token2049.

Prior to her work in Web3 and venture, Tsai held leadership roles across law, communications, and digital innovation. At CondΓ© Nast, she led strategic partnerships and product development, launching the VOGUE credit card and VIP membership program. At Isentia, she advised clients including Apple, LVMH, and Huawei on APAC expansion and crisis strategy, designing LLM-powered media intelligence systems used by executive teams. She began her career in high-tech litigation at DaVinci, a Taiwan-based law firm, and later led regional campaigns at Ogilvy for clients including Google, Seagate, Oracle, and Cheetah Mobile.

Tsai holds a law degree from National Taiwan University. Her work centers on enabling bold founders and institutions to scale breakthrough technologies across capital, compute, and collective action.

Featured Portfolio

Company Description Category
Render Network
Decentralized GPU rendering platform revolutionizing 3D content and AI compute, backed by industry titans Ari Emanuel and JJ Abrams
DePIN / AI Infrastructure
IO.net
Largest decentralized GPU network aggregating 30,000+ GPUs for AI/ML workloads, backed by Hack VC and Multicoin Capital
DePIN / AI Compute
0g Labs
First decentralized AI operating system with modular blockchain architecture, raised $35M from Hack VC, Animoca, Samsung NEXT
AI Infrastructure / L1
GAIB
Economic layer for AI compute tokenizing GPUs into yield-bearing assets, backed by Hack VC, launching first AI synthetic dollar
AI Finance / RWA
Jambo
Web3 super app bringing blockchain to emerging markets with $99 JamboPhone and ecosystem, backed by Paradigm in $30M Series A
Web3 / Infrastructure
Clearpool
Leading decentralized credit marketplace with $640M+ originated loans, backed by Sequoia Capital and Sino Global Capital
DeFi / Lending
SynFutures
Leading perpetual DEX with $34B+ volume, backed by Pantera, Polychain, Dragonfly, Standard Crypto, and Framework
DeFi / Derivatives
DeFi App
All-in-one DeFi SuperApp offering instant cross-chain swaps, yield farming, and perpetuals with zero gas fees
DeFi / Infrastructure
Zeus Network
Pioneering Bitcoin-Solana interoperability layer enabling permissionless BTC liquidity, processing $4.8M+ cross-chain volume
Cross-chain / Infrastructure
Solv Protocol
Tokenized fund platform bringing structured financial products like bonds and ETFs on-chain, recently partnered with Binance and raised $6M led by Nomura's Laser Digital
RWA / Asset Management
Shibuya
Decentralized streaming platform by NFT artist pplpleasr enabling viewer participation in content creation and governance
Media / Web3
Highstreet
Commerce-centered metaverse combining VR and phygital retail, backed by HTC and Mechanism Capital in $5M round
Metaverse / Gaming
Opulous
DeFi platform democratizing music financing through tokenized royalties, strategic partnership with LINE Corporation
DeFi / Music
Ethernity / Epic Chain
Layer 2 blockchain for entertainment and RWAs, partnering with global icons including Lionel Messi and Muhammad Ali
L2 / Entertainment
CG Oncology
NASDAQ-listed biotech developing breakthrough bladder cancer immunotherapy with 75%+ complete response rates, advancing toward FDA approval
Biotech / Public

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